Methionine Supplementation during Pregnancy of Goats Improves Kids’ Birth Weight, Body Mass Index, and Postnatal Growth Pattern

SIMPLE SUMMARY: Methionine is an essential amino acid that contributes to protein formation, fetal development, and milk synthesis. Thus, we hypothesized that a supplementation with Optimethione(®) during the last third of gestation in female goats will increase the maternal body live weight, the milk yield and milk composition and the offspring weight and body mass index at birth and postnatal performance. We fed (n = 30) or not (n = 30) herbal methionine Optimethione(®) to pregnant multiparous Alpine goats from gestational day 100 until delivery. We evaluated the productive variables from the dams and offspring. Maternal intake of herbal methionine Optimethione(®) during pregnancy did not increase the live weight or increase the milk yield and composition. However, the tested offspring variables were influenced by the maternal intake of herbal methionine Optimethione(®) during gestation by improving the birth weight, body mass index, and postnatal growth pattern. An increase in birth weight would be expected to increase neonatal survival up to weaning. Moreover, a relative fatness is required for reproductive success; thus, offspring that are born heavier and bigger can display a faster postnatal growth and accelerate the onset of puberty and increase reproductive success. ABSTRACT: The last third of gestation is a period of high energy and protein demand for the dam to support fetal growth and the following onset of lactation. Methionine is an essential amino acid that contributes to protein formation, fetal development, and milk synthesis; thus, is likely to have positive effects on the weight and size of the newborn and, afterward, milk yield and milk composition, which may improve growth patterns of the progeny. To test these hypotheses, we used 60 pregnant multiparous Alpine goats with similar live weights and gestational ages (~Day 100 of pregnancy; Mean ± SD; 1410 ± 14 days old and 50.4 ± 6.6 kg) and were separated into two groups: control and supplemented with the delivery. Treatments were T-MET (n = 30; received 1% herbal methionine Optimethione(®) dry matter based on from Day 100 of the pregnancy to delivery) or T-CTL (n = 30; served as the control and did not receive methionine). The methionine powder provided individual supplementation and was adjusted every week as the live weight and dry matter intake changed. At birth, the weight, body mass index (BMI), birth type, and sex of the kids were determined. Subsequently, the progeny was weighed weekly up to weaning. Two weeks after parturition, the milk composition was recorded weekly, and the milk yield was recorded monthly. The maternal live weight at the start (Mean ± SEM; T-CTL: 50.5 ± 1.1 vs. T-MET: 50.3 ± 1.3 kg) and end (T-CTL: 54.2 ± 1.3 vs. T-MET: 52.8 ± 1.4 kg) of the experiment did not differ statistically among treatments (p > 0.05); however, daily live weight changes tended to differ between groups (T-CTL: 73 ± 10 vs. T-MET: 51 ± 7 g day(−1); p = 0.06). The birth weight (T-CTL: 3.1 ± 0.1 vs. T-MET: 3.5 ± 0.1 kg; p < 0.001), daily live weight change (T-CTL: 121 ± 6 vs. T-MET: 141 ± 6 g day(−1); p < 0.01), and weaning weight (T-CTL: 8.3 ± 0.2 vs. T-MET: 9.3 ± 0.3 kg; p < 0.01) differed between treatments. The BMI at birth (T-CTL: 0.28 ± 0.01 vs. T-MET: 0.3 ± 0.01 units kg m(−2); p < 0.01) and at weaning (T-CTL: 0.85 ± 0.1 kg vs. T-MET: 1.00 ± 0.06 units kg m(−2); p < 0.05) differed between treatments. Milk components (protein, fat, lactose, and solids non-fat) and milk yield were similar between treatments (p > 0.05). It is concluded that the inclusion of methionine in the maternal goat diet during the last third of gestation increases the birth and growth variables of the progeny but without significant influence on the milk yield and composition.