Cargando…

High-Density Lipoprotein Changes in Alzheimer’s Disease Are APOE Genotype-Specific

High-density lipoproteins (HDL) play a critical role in cholesterol homeostasis. Apolipoprotein E (APOE), particularly the E4 allele, is a significant risk factor for Alzheimer’s disease but is also a key HDL-associated protein involved in lipid transport in both the periphery and central nervous sy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Brian V., Zheng, Jingyuan, Agus, Joanne K., Tang, Xinyu, Lebrilla, Carlito B., Jin, Lee-Way, Maezawa, Izumi, Erickson, Kelsey, Harvey, Danielle J., DeCarli, Charles S., Mungas, Dan M., Olichney, John M., Farias, Sarah T., Zivkovic, Angela M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312991/ https://www.ncbi.nlm.nih.gov/pubmed/35884800 http://dx.doi.org/10.3390/biomedicines10071495

Ejemplares similares

Glycosylation alterations in serum of Alzheimer's disease patients show widespread changes in N‐glycosylation of proteins related to immune function, inflammation, and lipoprotein metabolism
por: Tena, Jennyfer, et al.
Publicado: (2022)

Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer’s disease
por: Tang, Xinyu, et al.
Publicado: (2023)

Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume
por: Sapkota, Shraddha, et al.
Publicado: (2022)

Cholesterol, Amyloid Beta, Fructose, and LPS Influence ROS and ATP Concentrations and the Phagocytic Capacity of HMC3 Human Microglia Cell Line
por: Muñoz Herrera, Oscar M., et al.
Publicado: (2023)

Metabolic flux analysis of the neural cell glycocalyx reveals differential utilization of monosaccharides
por: Wong, Maurice, et al.
Publicado: (2020)

Prolonged Fasting Alters the Size, Function, and Glycoproteomic Profile of HDL Particles
por: Agus, Joanne, et al.
Publicado: (2022)

Regio-Specific N-Glycome and N-Glycoproteome Map of the Elderly Human Brain With and Without Alzheimer’s Disease
por: Tena, Jennyfer, et al.
Publicado: (2022)

Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers
por: Sapkota, Shraddha, et al.
Publicado: (2023)

Quantitative glycoproteomics of high-density lipoproteins
por: Tang, Xinyu, et al.
Publicado: (2022)

Glycomic Analysis of High Density Lipoprotein Shows a Highly Sialylated Particle
por: Huang, Jincui, et al.
Publicado: (2014)

Precision Nutrition and Cardiovascular Disease Risk Reduction: the Promise of High-Density Lipoproteins
por: Hong, Brian V., et al.
Publicado: (2023)

Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias
por: Mungas, Dan, et al.
Publicado: (2021)

Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses
por: Fletcher, Evan, et al.
Publicado: (2018)

Toward a statistical validation of brain signatures as robust measures of behavioral substrates
por: Fletcher, Evan, et al.
Publicado: (2023)

Isolation of HDL by sequential flotation ultracentrifugation followed by size exclusion chromatography reveals size-based enrichment of HDL-associated proteins
por: Zheng, Jack Jingyuan, et al.
Publicado: (2021)

Clinical and genetic analysis of lipoprotein glomerulopathy patients caused by APOE mutations
por: Yang, Mingxin, et al.
Publicado: (2020)

Lipid-Based Nutrient Supplementation Increases High-Density Lipoprotein (HDL) Cholesterol Efflux Capacity and Is Associated with Changes in the HDL Glycoproteome in Children
por: Hong, Brian V., et al.
Publicado: (2021)

Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice
por: Wu, Hongyan, et al.
Publicado: (2021)

Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme
por: Alfred, Tamuno, et al.
Publicado: (2014)

A single 36-h water-only fast vastly remodels the plasma lipidome
por: Hong, Brian V., et al.
Publicado: (2023)

Potential role of ATM in hepatocyte endocytosis of ApoE-deficient, ApoB48-containing lipoprotein in ApoE-deficient mice
por: WU, JIANHUA, et al.
Publicado: (2014)

Biosynthesis of lipoprotein: location of nascent apoAI and apoB in the rough endoplasmic reticulum of chicken hepatocytes
Publicado: (1992)

Polymorphism of Apo lipoprotein E gene and the risk of multiple sclerosis
por: Sadeghi, Hamid Mirmohammad, et al.
Publicado: (2011)

ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein
por: Mousa, Hanaa, et al.
Publicado: (2023)

Racial differences between African-American and white women in insulin resistance and visceral adiposity are associated with differences in apoCIII containing apoAI and apoB lipoproteins
por: Wang, Liyun, et al.
Publicado: (2014)

White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer’s disease (AD) neuropathology: A hypothesis and review
por: Sharp, Frank R., et al.
Publicado: (2023)

A Case of Lipoprotein Glomerulopathy with apoE Chicago and apoE (Glu3Lys) Treated with Fenofibrate
por: Kodera, Hitoshi, et al.
Publicado: (2017)

Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke
por: Chen, Yi‐Je, et al.
Publicado: (2017)

Developments in the Identification of Glycan Biomarkers for the Detection of Cancer
por: Ruhaak, L. Renee, et al.
Publicado: (2013)

Milk: A Scientific Model for Diet and Health Research in the 21st Century
por: German, J. Bruce, et al.
Publicado: (2022)

ApoA-I-Mediated Lipoprotein Remodeling Monitored with a Fluorescent Phospholipid
por: Neufeld, Edward B., et al.
Publicado: (2019)

SAA is Found on ApoB-Containing Lipoproteins in Obese Diabetic Humans
por: Jahangiri, Anisa, et al.
Publicado: (2013)

The Roles of ApoC-III on the Metabolism of Triglyceride-Rich Lipoproteins in Humans
por: Borén, Jan, et al.
Publicado: (2020)

Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice
por: Pouwer, Marianne G, et al.
Publicado: (2019)

ApoA-I/A-II-HDL positively associates with apoB-lipoproteins as a potential atherogenic indicator
por: Kido, Toshimi, et al.
Publicado: (2017)

Lifecourse socioeconomic changes and late-life cognition in a cohort of U.S.-born and U.S. immigrants: findings from the KHANDLE study
por: Peterson, Rachel L., et al.
Publicado: (2021)

Plasma Lecithin-Cholesterol Acyltransferase Activity in Pregnant Women Enrolled in the iLiNS-DYAD Trial in Ghana
por: Hong, Brian, et al.
Publicado: (2022)

Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of apoE(-/-)/LDL(-/- )double knockout mice
por: Langheinrich, Alexander C, et al.
Publicado: (2010)

In-Depth Method for the Characterization of Glycosylation in Manufactured Recombinant Monoclonal Antibody Drugs
por: Song, Ting, et al.
Publicado: (2014)

Characterization of Cell Glycocalyx with Mass Spectrometry Methods
por: Li, Qiongyu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_29v01akm9jus23ufgc8m4fdtpk