What Makes GPCRs from Different Families Bind to the Same Ligand?

G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins with important functions in signal transduction and often serve as therapeutic drug targets. With the rapidly growing public data on three dimensional (3D) structures of GPCRs and GPCR-ligand interactions, co...

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Detalles Bibliográficos
Autores principales: Dankwah, Kwabena Owusu, Mohl, Jonathon E., Begum, Khodeza, Leung, Ming-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313020/
https://www.ncbi.nlm.nih.gov/pubmed/35883418
http://dx.doi.org/10.3390/biom12070863

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