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Characteristics of Normalization Methods in Quantitative Urinary Metabolomics—Implications for Epidemiological Applications and Interpretations
A systematic comparison is presented for the effects of seven different normalization schemes in quantitative urinary metabolomics. Morning spot urine samples were analyzed with nuclear magnetic resonance (NMR) spectroscopy from a population-based group of 994 individuals. Forty-four metabolites wer...
Autores principales: | Li, Tianqi, Tynkkynen, Tuulia, Ihanus, Andrei, Zhao, Siyu, Mäkinen, Ville-Petteri, Ala-Korpela, Mika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313036/ https://www.ncbi.nlm.nih.gov/pubmed/35883459 http://dx.doi.org/10.3390/biom12070903 |
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