Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques

Effective antiretroviral therapy (ART) has transitioned HIV to a chronic disease, with more than 50% of people living with HIV (PLWH) being over the age of 50. HIV targets activated CD4(+) T cells expressing HIV-specific co-receptors (CCR5 and CXCR4). Previously, we reported that chronic binge alcoh...

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Detalles Bibliográficos
Autores principales: McTernan, Patrick M., Siggins, Robert W., Catinis, Anna, Amedee, Angela M., Simon, Liz, Molina, Patricia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313096/
https://www.ncbi.nlm.nih.gov/pubmed/35883501
http://dx.doi.org/10.3390/biom12070946

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