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Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection

Inflammatory diseases are some of the most common diseases in different parts of the world. So far, most attention has been paid to the role of environmental factors in the inflammatory process. The diagnosis of inflammatory changes is an important goal for the timely diagnosis and treatment of vari...

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Autores principales: Mousavi, Seyyed Mojtaba, Hashemi, Seyyed Alireza, Yari Kalashgrani, Masoomeh, Kurniawan, Darwin, Gholami, Ahmad, Rahmanian, Vahid, Omidifar, Navid, Chiang, Wei-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313165/
https://www.ncbi.nlm.nih.gov/pubmed/35884264
http://dx.doi.org/10.3390/bios12070461
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author Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Kurniawan, Darwin
Gholami, Ahmad
Rahmanian, Vahid
Omidifar, Navid
Chiang, Wei-Hung
author_facet Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Kurniawan, Darwin
Gholami, Ahmad
Rahmanian, Vahid
Omidifar, Navid
Chiang, Wei-Hung
author_sort Mousavi, Seyyed Mojtaba
collection PubMed
description Inflammatory diseases are some of the most common diseases in different parts of the world. So far, most attention has been paid to the role of environmental factors in the inflammatory process. The diagnosis of inflammatory changes is an important goal for the timely diagnosis and treatment of various metastatic, autoimmune, and infectious diseases. Graphene quantum dots (GQDs) can be used for the diagnosis of inflammation due to their excellent properties, such as high biocompatibility, low toxicity, high stability, and specific surface area. Additionally, surface-enhanced Raman spectroscopy (SERS) allows the very sensitive structural detection of analytes at low concentrations by amplifying electromagnetic fields generated by the excitation of localized surface plasmons. In recent years, the use of graphene quantum dots amplified by SERS has increased for the diagnosis of inflammation. The known advantages of graphene quantum dots SERS include non-destructive analysis methods, sensitivity and specificity, and the generation of narrow spectral bands characteristic of the molecular components present, which have led to their increased application. In this article, we review recent advances in the diagnosis of inflammation using graphene quantum dots and their improved detection of SERS. In this review study, the graphene quantum dots synthesis method, bioactivation method, inflammatory biomarkers, plasma synthesis of GQDs and SERS GQD are investigated. Finally, the detection mechanisms of SERS and the detection of inflammation are presented.
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spelling pubmed-93131652022-07-26 Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection Mousavi, Seyyed Mojtaba Hashemi, Seyyed Alireza Yari Kalashgrani, Masoomeh Kurniawan, Darwin Gholami, Ahmad Rahmanian, Vahid Omidifar, Navid Chiang, Wei-Hung Biosensors (Basel) Review Inflammatory diseases are some of the most common diseases in different parts of the world. So far, most attention has been paid to the role of environmental factors in the inflammatory process. The diagnosis of inflammatory changes is an important goal for the timely diagnosis and treatment of various metastatic, autoimmune, and infectious diseases. Graphene quantum dots (GQDs) can be used for the diagnosis of inflammation due to their excellent properties, such as high biocompatibility, low toxicity, high stability, and specific surface area. Additionally, surface-enhanced Raman spectroscopy (SERS) allows the very sensitive structural detection of analytes at low concentrations by amplifying electromagnetic fields generated by the excitation of localized surface plasmons. In recent years, the use of graphene quantum dots amplified by SERS has increased for the diagnosis of inflammation. The known advantages of graphene quantum dots SERS include non-destructive analysis methods, sensitivity and specificity, and the generation of narrow spectral bands characteristic of the molecular components present, which have led to their increased application. In this article, we review recent advances in the diagnosis of inflammation using graphene quantum dots and their improved detection of SERS. In this review study, the graphene quantum dots synthesis method, bioactivation method, inflammatory biomarkers, plasma synthesis of GQDs and SERS GQD are investigated. Finally, the detection mechanisms of SERS and the detection of inflammation are presented. MDPI 2022-06-27 /pmc/articles/PMC9313165/ /pubmed/35884264 http://dx.doi.org/10.3390/bios12070461 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Kurniawan, Darwin
Gholami, Ahmad
Rahmanian, Vahid
Omidifar, Navid
Chiang, Wei-Hung
Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title_full Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title_fullStr Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title_full_unstemmed Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title_short Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection
title_sort recent advances in inflammatory diagnosis with graphene quantum dots enhanced sers detection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313165/
https://www.ncbi.nlm.nih.gov/pubmed/35884264
http://dx.doi.org/10.3390/bios12070461
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