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Acute Effects of Focused Ultrasound-Induced Blood-Brain Barrier Opening on Anti-Pyroglu3 Abeta Antibody Delivery and Immune Responses
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid plaques and hyperphosphorylated tau in the brain. Currently, therapeutic agents targeting amyloid appear promising for AD, however, delivery to the CNS is limited due to the blood-brain-barrier (BBB...
Autores principales: | Bathini, Praveen, Sun, Tao, Schenk, Mathias, Schilling, Stephan, McDannold, Nathan J., Lemere, Cynthia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313174/ https://www.ncbi.nlm.nih.gov/pubmed/35883506 http://dx.doi.org/10.3390/biom12070951 |
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