Clinically Relevant Dose of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα), Lowers Serum Triglyceride Levels by Targeting Hepatic PPARα in Mice

Pemafibrate (PEM) is a novel lipid-lowering drug classified as a selective peroxisome proliferator-activated receptor α (PPARα) modulator whose binding efficiency to PPARα is superior to that of fibrates. This agent is also useful for non-alcoholic fatty liver disease and primary biliary cholangitis...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Diao, Pan, Zhang, Xuguang, Nakajima, Takero, Kimura, Takefumi, Tanaka, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313206/
https://www.ncbi.nlm.nih.gov/pubmed/35884970
http://dx.doi.org/10.3390/biomedicines10071667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313206/
https://www.ncbi.nlm.nih.gov/pubmed/35884970
http://dx.doi.org/10.3390/biomedicines10071667

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