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Mitochondrial Ribosome Dysfunction in Human Alveolar Type II Cells in Emphysema
Pulmonary emphysema is characterized by airspace enlargement and the destruction of alveoli. Alveolar type II (ATII) cells are very abundant in mitochondria. OXPHOS complexes are composed of proteins encoded by the mitochondrial and nuclear genomes. Mitochondrial 12S and 16S rRNAs are required to as...
Autores principales: | Karim, Loukmane, Lin, Chih-Ru, Kosmider, Beata, Criner, Gerard, Marchetti, Nathaniel, Bolla, Sudhir, Bowler, Russell, Bahmed, Karim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313339/ https://www.ncbi.nlm.nih.gov/pubmed/35884802 http://dx.doi.org/10.3390/biomedicines10071497 |
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