Cargando…

Large Area Microfluidic Bioreactor for Production of Recombinant Protein

To produce innovative biopharmaceuticals, highly flexible, adaptable, robust, and affordable bioprocess platforms for bioreactors are essential. In this article, we describe the development of a large-area microfluidic bioreactor (LM bioreactor) for mammalian cell culture that works at laminar flow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bourguignon, Natalia, Karp, Paola, Attallah, Carolina, Chamorro, Daniel A., Oggero, Marcos, Booth, Ross, Ferrero, Sol, Bhansali, Shekhar, Pérez, Maximiliano S., Lerner, Betiana, Helguera, Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313365/ https://www.ncbi.nlm.nih.gov/pubmed/35884329 http://dx.doi.org/10.3390/bios12070526

Ejemplares similares

Novel Reproducible Manufacturing and Reversible Sealing Method for Microfluidic Devices
por: Pérez-Sosa, Camilo, et al.
Publicado: (2022)

Single cell transfection of human-induced pluripotent stem cells using a droplet-based microfluidic system
por: Pérez-Sosa, Camilo, et al.
Publicado: (2022)

Development of image analysis software for quantification of viable cells in microchips
por: Georg, Maximilian, et al.
Publicado: (2018)

Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS
por: Gimenez, Rocio, et al.
Publicado: (2022)

GEMA—An Automatic Segmentation Method for Real-Time Analysis of Mammalian Cell Growth in Microfluidic Devices
por: Isa-Jara, Ramiro, et al.
Publicado: (2022)

Cost-effective fabrication of photopolymer molds with multi-level microstructures for PDMS microfluidic device manufacture
por: Olmos, Carol M., et al.
Publicado: (2020)

Hybrid microchannel-solid state micropore device for fast and optical cell detection
por: Olmos, Carol M., et al.
Publicado: (2020)

Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips
por: Ho, Phuong, et al.
Publicado: (2019)

Enhanced cryopreservation of MSCs in microfluidic bioreactor by regulated shear flow
por: Bissoyi, Akalabya, et al.
Publicado: (2016)

Plant Based Bioreactors of Recombinant Cytokines (Review)
por: Burlakovskiy, M. S., et al.
Publicado: (2016)

A modular microfluidic bioreactor to investigate plant cell–cell interactions
por: Finkbeiner, T., et al.
Publicado: (2021)

Expansion of cord blood stem cells in fibronectin-coated microfluidic bioreactor
por: Moghadasi, Mohamad Hossein, et al.
Publicado: (2022)

Dynamic Bayesian Networks for Integrating Multi-omics Time Series Microbiome Data
por: Ruiz-Perez, Daniel, et al.
Publicado: (2021)

Microfluidic Bioreactor Made of Cyclo-Olefin Polymer for Observing On-Chip Platelet Production
por: Kumon, Hiroki, et al.
Publicado: (2021)

Metronomic doses and drug schematic combination response tested within chambered coverslips for the treatment of breast cancer cells (JIMT-1)
por: Rosero, Gustavo, et al.
Publicado: (2022)

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation
por: Gruenberger, Alexander, et al.
Publicado: (2013)

A modular microfluidic bioreactor with improved throughput for evaluation of polarized renal epithelial cells
por: Brakeman, Paul, et al.
Publicado: (2016)

3D Printed Microfluidic Bioreactors Used for the Preferential Growth of Bacterial Biofilms through Dielectrophoresis
por: Csapai, Alexandra, et al.
Publicado: (2022)

Bioreactor-Scale Strategies for the Production of Recombinant Protein in the Yeast Yarrowia lipolytica
por: Vandermies, Marie, et al.
Publicado: (2019)

Transcriptome analysis of Corynebacterium glutamicum in the process of recombinant protein expression in bioreactors
por: Sun, Yang, et al.
Publicado: (2017)

A Microfluidic Bioreactor with in Situ SERS Imaging for the Study of Controlled Flow Patterns of Biofilm Precursor Materials
por: Paquet-Mercier, François, et al.
Publicado: (2013)

Production of Recombinant Human DNA Polymerase Delta in a Bombyx mori Bioreactor
por: Zhou, Yajing, et al.
Publicado: (2011)

Semicontinuous Bioreactor Production of Recombinant Butyrylcholinesterase in Transgenic Rice Cell Suspension Cultures
por: Corbin, Jasmine M., et al.
Publicado: (2016)

Synechococcus elongatus as a model of photosynthetic bioreactor for expression of recombinant β-glucosidases
por: Azevedo, Raíza, et al.
Publicado: (2019)

Automated microfluidic platform of bead-based electrochemical immunosensor integrated with bioreactor for continual monitoring of cell secreted biomarkers
por: Riahi, Reza, et al.
Publicado: (2016)

Integrated foam fractionation for heterologous rhamnolipid production with recombinant Pseudomonas putida in a bioreactor
por: Beuker, Janina, et al.
Publicado: (2016)

Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors
por: Etxeberria, Leire, et al.
Publicado: (2022)

A Macroporous Bioreactor Super Activated by the Recombinant Human Transforming Growth Factor-β(3)
por: Ripamonti, Ugo, et al.
Publicado: (2012)

Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors
por: Top, Oguz, et al.
Publicado: (2019)

Improved Production of Recombinant Human β-NGF in Escherichia coli – a Bioreactor Scale Study
por: HAJIHASSAN, ZAHRA, et al.
Publicado: (2018)

A method to simplify bioreactor processing for recombinant protein production in rice cell suspension cultures
por: Macharoen, Kantharakorn, et al.
Publicado: (2020)

fM to aM nucleic acid amplification for molecular diagnostics in a non-stick-coated metal microfluidic bioreactor
por: Huang, Guoliang, et al.
Publicado: (2014)

Bioreactors : design, operation and novel applications
Publicado: (2016)

Production of Recombinant Zika Virus Envelope Protein by Airlift Bioreactor as a New Subunit Vaccine Platform
por: da Costa, Hernan H. M., et al.
Publicado: (2023)

Bioreactor Scalability: Laboratory-Scale Bioreactor Design Influences Performance, Ecology, and Community Physiology in Expanded Granular Sludge Bed Bioreactors
por: Connelly, Stephanie, et al.
Publicado: (2017)

Bioreactors get personal
por: Somerville, Robert P.T., et al.
Publicado: (2012)

Transgenic animal bioreactors
por: Houdebine, Louis Marie
Publicado: (2000)

Carbon Nanotube Integration with a CMOS Process
por: Perez, Maximiliano S., et al.
Publicado: (2010)

High cell density cultivation and recombinant protein production with Escherichia coli in a rocking-motion-type bioreactor
por: Glazyrina, Julia, et al.
Publicado: (2010)

Integrating human stem cell expansion and neuronal differentiation in bioreactors
por: Serra, Margarida, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6cvm59o1ocfumio45vg8vrev78