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Tracking Clonal Evolution of Multiple Myeloma Using Targeted Next-Generation DNA Sequencing

Clonal evolution drives treatment failure in multiple myeloma (MM). Here, we used a custom 372-gene panel to track genetic changes occurring during MM progression at different stages of the disease. A tumor-only targeted next-generation DNA sequencing was performed on 69 samples sequentially collect...

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Detalles Bibliográficos
Autores principales: Salomon-Perzyński, Aleksander, Barankiewicz, Joanna, Machnicki, Marcin, Misiewicz-Krzemińska, Irena, Pawlak, Michał, Radomska, Sylwia, Krzywdzińska, Agnieszka, Bluszcz, Aleksandra, Stawiński, Piotr, Rydzanicz, Małgorzata, Jakacka, Natalia, Solarska, Iwona, Borg, Katarzyna, Spyra-Górny, Zofia, Szpila, Tomasz, Puła, Bartosz, Grosicki, Sebastian, Stokłosa, Tomasz, Płoski, Rafał, Lech-Marańda, Ewa, Jakubikova, Jana, Jamroziak, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313382/
https://www.ncbi.nlm.nih.gov/pubmed/35884979
http://dx.doi.org/10.3390/biomedicines10071674