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Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study

Attention-deficit/hyperactivity disorder (ADHD) is a persistent neurodevelopmental disorder that results from complex interactions of multiple genes and environmental risk and adversity factors. Some researchers have suggested a need for additional research into differing clinical presentations of A...

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Autores principales: Streeter, Brooke, Sadek, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313383/
https://www.ncbi.nlm.nih.gov/pubmed/35884726
http://dx.doi.org/10.3390/brainsci12070919
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author Streeter, Brooke
Sadek, Joseph
author_facet Streeter, Brooke
Sadek, Joseph
author_sort Streeter, Brooke
collection PubMed
description Attention-deficit/hyperactivity disorder (ADHD) is a persistent neurodevelopmental disorder that results from complex interactions of multiple genes and environmental risk and adversity factors. Some researchers have suggested a need for additional research into differing clinical presentations of ADHD for further classification. In this context, this study aimed to investigate whether increases in risk and adversity factors increase the severity of ADHD and the number of comorbid psychiatric disorders. This is a naturalistic retrospective chart review exploratory study in 100 patients 16 years or older who have a confirmed diagnosis of ADHD. The quantitative data were analyzed using SPSS, using the Mann–Whitney test for parametric data and the Chi-square and Kruskal–Wallis p value tests for non-parametric and categorical data. Qualitative data were tabulated and described. The study found that (1) the average number of comorbidities increases with the severity of ADHD, (2) the average number of risk and adversity factors increases with the severity of ADHD, (3) the number of risk and adversity factors were positively associated with the number of comorbidities, and (4) Level of education was negatively associated with the number of risk and adversity factors and the number of comorbidities. The implications of these findings are discussed, and future research in this important area is suggested.
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spelling pubmed-93133832022-07-26 Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study Streeter, Brooke Sadek, Joseph Brain Sci Article Attention-deficit/hyperactivity disorder (ADHD) is a persistent neurodevelopmental disorder that results from complex interactions of multiple genes and environmental risk and adversity factors. Some researchers have suggested a need for additional research into differing clinical presentations of ADHD for further classification. In this context, this study aimed to investigate whether increases in risk and adversity factors increase the severity of ADHD and the number of comorbid psychiatric disorders. This is a naturalistic retrospective chart review exploratory study in 100 patients 16 years or older who have a confirmed diagnosis of ADHD. The quantitative data were analyzed using SPSS, using the Mann–Whitney test for parametric data and the Chi-square and Kruskal–Wallis p value tests for non-parametric and categorical data. Qualitative data were tabulated and described. The study found that (1) the average number of comorbidities increases with the severity of ADHD, (2) the average number of risk and adversity factors increases with the severity of ADHD, (3) the number of risk and adversity factors were positively associated with the number of comorbidities, and (4) Level of education was negatively associated with the number of risk and adversity factors and the number of comorbidities. The implications of these findings are discussed, and future research in this important area is suggested. MDPI 2022-07-13 /pmc/articles/PMC9313383/ /pubmed/35884726 http://dx.doi.org/10.3390/brainsci12070919 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Streeter, Brooke
Sadek, Joseph
Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title_full Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title_fullStr Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title_full_unstemmed Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title_short Developmental Risk, Adversity Experiences and ADHD Clinical Profiles: A Naturalistic Exploratory Study
title_sort developmental risk, adversity experiences and adhd clinical profiles: a naturalistic exploratory study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313383/
https://www.ncbi.nlm.nih.gov/pubmed/35884726
http://dx.doi.org/10.3390/brainsci12070919
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