Cargando…

P63 and P73 Activation in Cancers with p53 Mutation

The members of the p53 family comprise p53, p63, and p73, and full-length isoforms of the p53 family have a tumor suppressor function. However, p53, but not p63 or p73, has a high mutation rate in cancers causing it to lose its tumor suppressor function. The top and second-most prevalent p53 mutatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Bi-He, Hsu, Yun-Chien, Yeh, Fang-Yu, Lin, Yu-Rou, Lu, Rui-Yu, Yu, Si-Jie, Shaw, Jei-Fu, Wu, Ming-Han, Tsai, Yi-Zhen, Lin, Ying-Chen, Bai, Zhi-Yu, Shih, Yu-Chen, Hsu, Yi-Chiang, Liao, Ruo-Yu, Kuo, Wei-Hsin, Hsu, Chao-Tien, Lien, Ching-Feng, Chen, Chia-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313412/
https://www.ncbi.nlm.nih.gov/pubmed/35884795
http://dx.doi.org/10.3390/biomedicines10071490