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P63 and P73 Activation in Cancers with p53 Mutation
The members of the p53 family comprise p53, p63, and p73, and full-length isoforms of the p53 family have a tumor suppressor function. However, p53, but not p63 or p73, has a high mutation rate in cancers causing it to lose its tumor suppressor function. The top and second-most prevalent p53 mutatio...
Autores principales: | Cai, Bi-He, Hsu, Yun-Chien, Yeh, Fang-Yu, Lin, Yu-Rou, Lu, Rui-Yu, Yu, Si-Jie, Shaw, Jei-Fu, Wu, Ming-Han, Tsai, Yi-Zhen, Lin, Ying-Chen, Bai, Zhi-Yu, Shih, Yu-Chen, Hsu, Yi-Chiang, Liao, Ruo-Yu, Kuo, Wei-Hsin, Hsu, Chao-Tien, Lien, Ching-Feng, Chen, Chia-Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313412/ https://www.ncbi.nlm.nih.gov/pubmed/35884795 http://dx.doi.org/10.3390/biomedicines10071490 |
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