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Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, classically associated with extensive loss of dopaminergic neurons of the substantia nigra pars compacta. The hallmark of the disease is the accumulation of pathogenic conformations of the presynaptic protein, α-synuclein...

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Detalles Bibliográficos
Autores principales: Akrioti, Elissavet, Karamitros, Timokratis, Gkaravelas, Panagiotis, Kouroupi, Georgia, Matsas, Rebecca, Taoufik, Era
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313424/
https://www.ncbi.nlm.nih.gov/pubmed/35883433
http://dx.doi.org/10.3390/biom12070876

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