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The Hypertensive Effect of Amphotericin B-Containing Liposomes (Abelcet) in Mice: Dissecting the Roles of C3a and C5a Anaphylatoxins, Macrophages and Thromboxane

Liposomal amphotericin B (Abelcet) can cause infusion (anaphylactoid) reactions in patients whose mechanism is poorly understood. Here, we used mice to investigate the role of complement (C) receptors and the cellular sources of vasoactive mediators in these reactions. Anesthetized male NMRI and thr...

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Detalles Bibliográficos
Autores principales: Őrfi, Erik, Hricisák, László, Dézsi, László, Hamar, Péter, Benyó, Zoltán, Szebeni, János, Szénási, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313435/
https://www.ncbi.nlm.nih.gov/pubmed/35885068
http://dx.doi.org/10.3390/biomedicines10071764

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