Functionalized Macrophage Exosomes with Panobinostat and PPM1D‐siRNA for Diffuse Intrinsic Pontine Gliomas Therapy

Diffuse intrinsic pontine glioma (DIPG) is a rare and fatal pediatric brain tumor. Mutation of p53‐induced protein phosphatase 1 (PPM1D) in DIPG cells promotes tumor cell proliferation, and inhibition of PPM1D expression in DIPG cells with PPM1D mutation effectively reduces the proliferation activit...

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Detalles Bibliográficos
Autores principales: Shan, Shaobo, Chen, Junge, Sun, Yu, Wang, Yongchao, Xia, Bozhang, Tan, Hong, Pan, Changcun, Gu, Guocan, Zhong, Jie, Qing, Guangchao, Zhang, Yuxuan, Wang, Jinjin, Wang, Yufei, Wang, Yi, Zuo, Pengcheng, Xu, Cheng, Li, Fangzhou, Guo, Weisheng, Xu, Lijun, Chen, Meiwan, Fan, Yubo, Zhang, Liwei, Liang, Xing‐Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313473/
https://www.ncbi.nlm.nih.gov/pubmed/35585670
http://dx.doi.org/10.1002/advs.202200353

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