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Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022)
Human Mesenchymal Stem Cell‐Derived Miniature Joint System In article number 2105909 by Rocky S. Tuan, Hang Lin, and co‐workers, a miniature synovial joint‐mimicking system (miniJoint) is established in a microfluidics‐enabled bioreactor, in which human mesenchymal stem cell‐derived bone‐cartilage c...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313541/ http://dx.doi.org/10.1002/advs.202270133 |
| _version_ | 1784754104599314432 |
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| author | Li, Zhong Lin, Zixuan Liu, Silvia Yagi, Haruyo Zhang, Xiurui Yocum, Lauren Romero‐Lopez, Monica Rhee, Claire Makarcyzk, Meagan J. Yu, Ilhan Li, Eileen N. Fritch, Madalyn R. Gao, Qi Goh, Kek Boon O'Donnell, Benjamen Hao, Tingjun Alexander, Peter G. Mahadik, Bhushan Fisher, John P. Goodman, Stuart B. Bunnell, Bruce A. Tuan, Rocky S. Lin, Hang |
| author_facet | Li, Zhong Lin, Zixuan Liu, Silvia Yagi, Haruyo Zhang, Xiurui Yocum, Lauren Romero‐Lopez, Monica Rhee, Claire Makarcyzk, Meagan J. Yu, Ilhan Li, Eileen N. Fritch, Madalyn R. Gao, Qi Goh, Kek Boon O'Donnell, Benjamen Hao, Tingjun Alexander, Peter G. Mahadik, Bhushan Fisher, John P. Goodman, Stuart B. Bunnell, Bruce A. Tuan, Rocky S. Lin, Hang |
| author_sort | Li, Zhong |
| collection | PubMed |
| description | Human Mesenchymal Stem Cell‐Derived Miniature Joint System In article number 2105909 by Rocky S. Tuan, Hang Lin, and co‐workers, a miniature synovial joint‐mimicking system (miniJoint) is established in a microfluidics‐enabled bioreactor, in which human mesenchymal stem cell‐derived bone‐cartilage complex, synovial‐like fibrous tissue, and adipose tissue are integrated and show active crosstalk. The data demonstrate the potential of miniJoint as a new model for the study of joint pathology and the development of novel therapeutic interventions. [Image: see text] |
| format | Online Article Text |
| id | pubmed-9313541 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-93135412022-07-27 Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) Li, Zhong Lin, Zixuan Liu, Silvia Yagi, Haruyo Zhang, Xiurui Yocum, Lauren Romero‐Lopez, Monica Rhee, Claire Makarcyzk, Meagan J. Yu, Ilhan Li, Eileen N. Fritch, Madalyn R. Gao, Qi Goh, Kek Boon O'Donnell, Benjamen Hao, Tingjun Alexander, Peter G. Mahadik, Bhushan Fisher, John P. Goodman, Stuart B. Bunnell, Bruce A. Tuan, Rocky S. Lin, Hang Adv Sci (Weinh) Back Cover Human Mesenchymal Stem Cell‐Derived Miniature Joint System In article number 2105909 by Rocky S. Tuan, Hang Lin, and co‐workers, a miniature synovial joint‐mimicking system (miniJoint) is established in a microfluidics‐enabled bioreactor, in which human mesenchymal stem cell‐derived bone‐cartilage complex, synovial‐like fibrous tissue, and adipose tissue are integrated and show active crosstalk. The data demonstrate the potential of miniJoint as a new model for the study of joint pathology and the development of novel therapeutic interventions. [Image: see text] John Wiley and Sons Inc. 2022-07-25 /pmc/articles/PMC9313541/ http://dx.doi.org/10.1002/advs.202270133 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Back Cover Li, Zhong Lin, Zixuan Liu, Silvia Yagi, Haruyo Zhang, Xiurui Yocum, Lauren Romero‐Lopez, Monica Rhee, Claire Makarcyzk, Meagan J. Yu, Ilhan Li, Eileen N. Fritch, Madalyn R. Gao, Qi Goh, Kek Boon O'Donnell, Benjamen Hao, Tingjun Alexander, Peter G. Mahadik, Bhushan Fisher, John P. Goodman, Stuart B. Bunnell, Bruce A. Tuan, Rocky S. Lin, Hang Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title | Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title_full | Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title_fullStr | Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title_full_unstemmed | Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title_short | Human Mesenchymal Stem Cell‐Derived Miniature Joint System for Disease Modeling and Drug Testing (Adv. Sci. 21/2022) |
| title_sort | human mesenchymal stem cell‐derived miniature joint system for disease modeling and drug testing (adv. sci. 21/2022) |
| topic | Back Cover |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313541/ http://dx.doi.org/10.1002/advs.202270133 |
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