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Expression of p53 protein isoforms predicts survival in patients with multiple myeloma

Loss and/or mutation of the TP53 gene are associated with short survival in multiple myeloma, but the p53 landscape goes far beyond. At least 12 p53 protein isoforms have been identified as a result of a combination of alternative splicing, alternative promoters and/or alternative transcription site...

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Detalles Bibliográficos
Autores principales: Rojas, Elizabeta A., Corchete, Luis A., De Ramón, Cristina, Krzeminski, Patryk, Quwaider, Dalia, García‐Sanz, Ramón, Martínez‐López, Joaquín, Oriol, Albert, Rosiñol, Laura, Bladé, Joan, Lahuerta, Juan José, San Miguel, Jesús F., González, Marcos, Mateos, María Victoria, Bourdon, Jean‐Christophe, Misiewicz‐Krzeminska, Irena, Gutiérrez, Norma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313569/
https://www.ncbi.nlm.nih.gov/pubmed/35188691
http://dx.doi.org/10.1002/ajh.26507