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Whole genome sequencing identifies rare genetic variants in familial pancreatic cancer patients

Pancreatic ductal adenocarcinoma (PDAC) represents one of the most lethal malignancies with very high mortality and short survival time. About 5–10% of the PDAC patients have a familial predisposition to the disease designated as familial pancreatic cancer (FPC), suggesting genetic modulation of FPC...

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Detalles Bibliográficos
Autores principales: Tan, Ming, Brusgaard, Klaus, Gerdes, Anne‐Marie, Larsen, Martin Jakob, Mortensen, Michael Bau, Detlefsen, Sönke, de Muckadell, Ove B. Schaffalitzky, Joergensen, Maiken Thyregod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313800/
https://www.ncbi.nlm.nih.gov/pubmed/35312039
http://dx.doi.org/10.1111/ahg.12464

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