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Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma

OBJECTIVES: Both peripherally inserted central catheters (PICCs) and implanted port catheters (PORTs) are commonly used for the delivery of immunochemotherapy. We compared the safety of the two types of devices in a homogeneous and monocentric population of diffuse large B‐cell lymphoma (DLBCL) pati...

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Autores principales: Pénichoux, Juliette, Rio, Julien, Kammoun, Leila, Vermeulin, Thomas, Pepin, Louis‐Ferdinand, Camus, Vincent, Dubois, Sydney, Bouclet, Florian, Alani, Mustafa, Contentin, Nathalie, Leprêtre, Stéphane, Stamatoullas, Aspasia, Lanic, Hélène, Lemasle, Emilie, Ménard, Anne‐Lise, Lenain, Pascal, Gilles‐Baray, Marie, Georgescu, Dragos, Clatot, Florian, Tilly, Hervé, Jardin, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313835/
https://www.ncbi.nlm.nih.gov/pubmed/35285085
http://dx.doi.org/10.1111/ejh.13767
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author Pénichoux, Juliette
Rio, Julien
Kammoun, Leila
Vermeulin, Thomas
Pepin, Louis‐Ferdinand
Camus, Vincent
Dubois, Sydney
Bouclet, Florian
Alani, Mustafa
Contentin, Nathalie
Leprêtre, Stéphane
Stamatoullas, Aspasia
Lanic, Hélène
Lemasle, Emilie
Ménard, Anne‐Lise
Lenain, Pascal
Gilles‐Baray, Marie
Georgescu, Dragos
Clatot, Florian
Tilly, Hervé
Jardin, Fabrice
author_facet Pénichoux, Juliette
Rio, Julien
Kammoun, Leila
Vermeulin, Thomas
Pepin, Louis‐Ferdinand
Camus, Vincent
Dubois, Sydney
Bouclet, Florian
Alani, Mustafa
Contentin, Nathalie
Leprêtre, Stéphane
Stamatoullas, Aspasia
Lanic, Hélène
Lemasle, Emilie
Ménard, Anne‐Lise
Lenain, Pascal
Gilles‐Baray, Marie
Georgescu, Dragos
Clatot, Florian
Tilly, Hervé
Jardin, Fabrice
author_sort Pénichoux, Juliette
collection PubMed
description OBJECTIVES: Both peripherally inserted central catheters (PICCs) and implanted port catheters (PORTs) are commonly used for the delivery of immunochemotherapy. We compared the safety of the two types of devices in a homogeneous and monocentric population of diffuse large B‐cell lymphoma (DLBCL) patients who were treated with first‐line immunochemotherapy by evaluating the numbers of catheter‐related venous thromboses (VTs) and infections that occurred in the six months after implantation according to the type of device. METHODS: Using a propensity score, the adjusted relative risk (ARR) between the type of catheter and the occurrence of catheter‐related complications (infection and/or VT) of interest was retrospectively determined. RESULTS: 479 patients were enrolled (266 PORTs/213 PICCs), and 26 VTs (5.4%) and 30 infections (6.3%) were identified in the period following PICC/PORT implantation. The adjusted relative risk (ARR) of catheter‐related complications (infection and/or VT) according to the type of device was 2.6 (95% CI =1.3–5.9, p = .0075). This risk increase associated with the PICC device was significant for both infections (ARR = 3.2; 95% CI = 1.3–10.9) and thrombosis (ARR = 4; 95% CI = 1.5–11.6). CONCLUSION: Our study supports the preferential use of PORTs for the first line of treatment for DLBCL patients.
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spelling pubmed-93138352022-07-30 Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma Pénichoux, Juliette Rio, Julien Kammoun, Leila Vermeulin, Thomas Pepin, Louis‐Ferdinand Camus, Vincent Dubois, Sydney Bouclet, Florian Alani, Mustafa Contentin, Nathalie Leprêtre, Stéphane Stamatoullas, Aspasia Lanic, Hélène Lemasle, Emilie Ménard, Anne‐Lise Lenain, Pascal Gilles‐Baray, Marie Georgescu, Dragos Clatot, Florian Tilly, Hervé Jardin, Fabrice Eur J Haematol Original Articles OBJECTIVES: Both peripherally inserted central catheters (PICCs) and implanted port catheters (PORTs) are commonly used for the delivery of immunochemotherapy. We compared the safety of the two types of devices in a homogeneous and monocentric population of diffuse large B‐cell lymphoma (DLBCL) patients who were treated with first‐line immunochemotherapy by evaluating the numbers of catheter‐related venous thromboses (VTs) and infections that occurred in the six months after implantation according to the type of device. METHODS: Using a propensity score, the adjusted relative risk (ARR) between the type of catheter and the occurrence of catheter‐related complications (infection and/or VT) of interest was retrospectively determined. RESULTS: 479 patients were enrolled (266 PORTs/213 PICCs), and 26 VTs (5.4%) and 30 infections (6.3%) were identified in the period following PICC/PORT implantation. The adjusted relative risk (ARR) of catheter‐related complications (infection and/or VT) according to the type of device was 2.6 (95% CI =1.3–5.9, p = .0075). This risk increase associated with the PICC device was significant for both infections (ARR = 3.2; 95% CI = 1.3–10.9) and thrombosis (ARR = 4; 95% CI = 1.5–11.6). CONCLUSION: Our study supports the preferential use of PORTs for the first line of treatment for DLBCL patients. John Wiley and Sons Inc. 2022-03-21 2022-07 /pmc/articles/PMC9313835/ /pubmed/35285085 http://dx.doi.org/10.1111/ejh.13767 Text en © 2022 The Authors. European Journal of Haematology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Pénichoux, Juliette
Rio, Julien
Kammoun, Leila
Vermeulin, Thomas
Pepin, Louis‐Ferdinand
Camus, Vincent
Dubois, Sydney
Bouclet, Florian
Alani, Mustafa
Contentin, Nathalie
Leprêtre, Stéphane
Stamatoullas, Aspasia
Lanic, Hélène
Lemasle, Emilie
Ménard, Anne‐Lise
Lenain, Pascal
Gilles‐Baray, Marie
Georgescu, Dragos
Clatot, Florian
Tilly, Hervé
Jardin, Fabrice
Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title_full Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title_fullStr Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title_full_unstemmed Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title_short Retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large B‐cell lymphoma
title_sort retrospective analysis of the safety of peripherally inserted catheters versus implanted port catheters during first‐line treatment for patients with diffuse large b‐cell lymphoma
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313835/
https://www.ncbi.nlm.nih.gov/pubmed/35285085
http://dx.doi.org/10.1111/ejh.13767
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