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DoE‐Driven Development of an Organocatalytic Enantioselective Addition of Acetaldehyde to Nitrostyrenes in Water

The development of an enantioselective enamine‐catalysed addition of masked acetaldehyde to nitroalkenes via a rational approach helped to move away from the use of chloroform. The presented research allows the use of water as a reaction medium, therefore improving the industrial relevance of a prot...

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Detalles Bibliográficos
Autores principales: Nori, Valeria, Sinibaldi, Arianna, Giorgianni, Giuliana, Pesciaioli, Fabio, Di Donato, Francesca, Cocco, Emanuele, Biancolillo, Alessandra, Landa, Aitor, Carlone, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313880/
https://www.ncbi.nlm.nih.gov/pubmed/35230722
http://dx.doi.org/10.1002/chem.202104524