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DoE‐Driven Development of an Organocatalytic Enantioselective Addition of Acetaldehyde to Nitrostyrenes in Water
The development of an enantioselective enamine‐catalysed addition of masked acetaldehyde to nitroalkenes via a rational approach helped to move away from the use of chloroform. The presented research allows the use of water as a reaction medium, therefore improving the industrial relevance of a prot...
Autores principales: | Nori, Valeria, Sinibaldi, Arianna, Giorgianni, Giuliana, Pesciaioli, Fabio, Di Donato, Francesca, Cocco, Emanuele, Biancolillo, Alessandra, Landa, Aitor, Carlone, Armando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313880/ https://www.ncbi.nlm.nih.gov/pubmed/35230722 http://dx.doi.org/10.1002/chem.202104524 |
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