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Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy

In March 2021, Italian health authorities suspended the Vaxzevria vaccine (VA) for 4 days over reports of very rare blood disorders among recipients. We exploit the quasi‐experimental setting arising from this break to study the drivers of vaccine hesitancy. Before the suspension, the VA vaccination...

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Autores principales: Deiana, Claudio, Geraci, Andrea, Mazzarella, Gianluca, Sabatini, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314121/
https://www.ncbi.nlm.nih.gov/pubmed/35318762
http://dx.doi.org/10.1002/hec.4506
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author Deiana, Claudio
Geraci, Andrea
Mazzarella, Gianluca
Sabatini, Fabio
author_facet Deiana, Claudio
Geraci, Andrea
Mazzarella, Gianluca
Sabatini, Fabio
author_sort Deiana, Claudio
collection PubMed
description In March 2021, Italian health authorities suspended the Vaxzevria vaccine (VA) for 4 days over reports of very rare blood disorders among recipients. We exploit the quasi‐experimental setting arising from this break to study the drivers of vaccine hesitancy. Before the suspension, the VA vaccination trend followed the same pattern as Pfizer‐Biontech (PB). After the suspension, VA and PB injections started to diverge, with VA daily decreasing by almost 60 doses per 100,000 inhabitants for the following 3 weeks. The resulting vaccination rate was 60 percent lower than the value that would have stemmed from the VA pre‐suspension pattern. We show that the slowdown was weaker and less persistent in regions with higher COVID penetration and steadier and more pronounced in regions displaying greater attention to vaccine side effects as detected through Google searches. The public's interest in vaccine adverse events negatively correlates with COVID cases and deaths across regions.
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spelling pubmed-93141212022-07-30 Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy Deiana, Claudio Geraci, Andrea Mazzarella, Gianluca Sabatini, Fabio Health Econ SHORT RESEARCH ARTICLES In March 2021, Italian health authorities suspended the Vaxzevria vaccine (VA) for 4 days over reports of very rare blood disorders among recipients. We exploit the quasi‐experimental setting arising from this break to study the drivers of vaccine hesitancy. Before the suspension, the VA vaccination trend followed the same pattern as Pfizer‐Biontech (PB). After the suspension, VA and PB injections started to diverge, with VA daily decreasing by almost 60 doses per 100,000 inhabitants for the following 3 weeks. The resulting vaccination rate was 60 percent lower than the value that would have stemmed from the VA pre‐suspension pattern. We show that the slowdown was weaker and less persistent in regions with higher COVID penetration and steadier and more pronounced in regions displaying greater attention to vaccine side effects as detected through Google searches. The public's interest in vaccine adverse events negatively correlates with COVID cases and deaths across regions. John Wiley and Sons Inc. 2022-03-22 2022-06 /pmc/articles/PMC9314121/ /pubmed/35318762 http://dx.doi.org/10.1002/hec.4506 Text en © 2022 The Authors. Health Economics published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle SHORT RESEARCH ARTICLES
Deiana, Claudio
Geraci, Andrea
Mazzarella, Gianluca
Sabatini, Fabio
Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title_full Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title_fullStr Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title_full_unstemmed Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title_short Perceived risk and vaccine hesitancy: Quasi‐experimental evidence from Italy
title_sort perceived risk and vaccine hesitancy: quasi‐experimental evidence from italy
topic SHORT RESEARCH ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314121/
https://www.ncbi.nlm.nih.gov/pubmed/35318762
http://dx.doi.org/10.1002/hec.4506
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