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The Association of Epstein-Barr Virus With Cancer

Epstein-Barr virus (EBV) is classified as a herpesvirus and is known for being one of the few viruses that can lead to the development of cancer. This study has gathered several studies to provide evidence as to this association as well as some of the mechanisms specific to EBV that allow this to ha...

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Autores principales: Patel, Pragnesh D, Alghareeb, Rahmah, Hussain, Afshan, Maheshwari, Marvi V, Khalid, Nabeeha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314235/
https://www.ncbi.nlm.nih.gov/pubmed/35911302
http://dx.doi.org/10.7759/cureus.26314
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author Patel, Pragnesh D
Alghareeb, Rahmah
Hussain, Afshan
Maheshwari, Marvi V
Khalid, Nabeeha
author_facet Patel, Pragnesh D
Alghareeb, Rahmah
Hussain, Afshan
Maheshwari, Marvi V
Khalid, Nabeeha
author_sort Patel, Pragnesh D
collection PubMed
description Epstein-Barr virus (EBV) is classified as a herpesvirus and is known for being one of the few viruses that can lead to the development of cancer. This study has gathered several studies to provide evidence as to this association as well as some of the mechanisms specific to EBV that allow this to happen. The development of EBV into cancer as well as the proteins involved in this oncogenesis play a crucial role in understanding this problem as well as creating a solution for mitigating this disease process in the future. This study summarized three of the most common malignancies caused by EBV in order to consolidate information about each of them. Additional emphasis was placed on finding which EBV serum markers were seen to be most indicative of prognosis and likelihood of developing malignancy. Higher serum EBV viral DNA loads were seen to be a useful indicator in assessing the risk of various cancers and should be studied further in relation to cancers that were not mentioned in this review.
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spelling pubmed-93142352022-07-29 The Association of Epstein-Barr Virus With Cancer Patel, Pragnesh D Alghareeb, Rahmah Hussain, Afshan Maheshwari, Marvi V Khalid, Nabeeha Cureus Internal Medicine Epstein-Barr virus (EBV) is classified as a herpesvirus and is known for being one of the few viruses that can lead to the development of cancer. This study has gathered several studies to provide evidence as to this association as well as some of the mechanisms specific to EBV that allow this to happen. The development of EBV into cancer as well as the proteins involved in this oncogenesis play a crucial role in understanding this problem as well as creating a solution for mitigating this disease process in the future. This study summarized three of the most common malignancies caused by EBV in order to consolidate information about each of them. Additional emphasis was placed on finding which EBV serum markers were seen to be most indicative of prognosis and likelihood of developing malignancy. Higher serum EBV viral DNA loads were seen to be a useful indicator in assessing the risk of various cancers and should be studied further in relation to cancers that were not mentioned in this review. Cureus 2022-06-25 /pmc/articles/PMC9314235/ /pubmed/35911302 http://dx.doi.org/10.7759/cureus.26314 Text en Copyright © 2022, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Patel, Pragnesh D
Alghareeb, Rahmah
Hussain, Afshan
Maheshwari, Marvi V
Khalid, Nabeeha
The Association of Epstein-Barr Virus With Cancer
title The Association of Epstein-Barr Virus With Cancer
title_full The Association of Epstein-Barr Virus With Cancer
title_fullStr The Association of Epstein-Barr Virus With Cancer
title_full_unstemmed The Association of Epstein-Barr Virus With Cancer
title_short The Association of Epstein-Barr Virus With Cancer
title_sort association of epstein-barr virus with cancer
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314235/
https://www.ncbi.nlm.nih.gov/pubmed/35911302
http://dx.doi.org/10.7759/cureus.26314
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