A secretory form of Parkin‐independent mitophagy contributes to the repertoire of extracellular vesicles released into the tumour interstitial fluid in vivo

We characterized the in vivo interstitial fluid (IF) content of extracellular vesicles (EVs) using the GFP‐4T1 syngeneic murine cancer model to study EVs in‐transit to the draining lymph node. GFP labelling confirmed the IF EV tumour cell origin. Molecular analysis revealed an abundance of IF EV‐ass...

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Detalles Bibliográficos
Autores principales: Howard, Marissa, Erickson, James, Cuba, Zachary, Kim, Shawn, Zhou, Weidong, Gade, Purva, Carter, Rachel, Mitchell, Kelsey, Branscome, Heather, Siddhi, Daivik, Alanazi, Fatimah, Kim, Yuriy, Araujo, Robyn P., Haymond, Amanda, Luchini, Alessandra, Kashanchi, Fatah, Liotta, Lance A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314315/
https://www.ncbi.nlm.nih.gov/pubmed/35879267
http://dx.doi.org/10.1002/jev2.12244

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