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KSTAR: An algorithm to predict patient-specific kinase activities from phosphoproteomic data
Kinase inhibitors as targeted therapies have played an important role in improving cancer outcomes. However, there are still considerable challenges, such as resistance, non-response, patient stratification, polypharmacology, and identifying combination therapy where understanding a tumor kinase act...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314348/ https://www.ncbi.nlm.nih.gov/pubmed/35879309 http://dx.doi.org/10.1038/s41467-022-32017-5 |