Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts

Mitochondria are highly dynamic organelles whose fragmentation by fission is critical to their functional integrity and cellular homeostasis. Here, we develop a method via optogenetic control of mitochondria–lysosome contacts (MLCs) to induce mitochondrial fission with spatiotemporal accuracy. MLCs...

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Detalles Bibliográficos
Autores principales: Qiu, Kangqiang, Zou, Weiwei, Fang, Hongbao, Hao, Mingang, Mehta, Kritika, Tian, Zhiqi, Guan, Jun-Lin, Zhang, Kai, Huang, Taosheng, Diao, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314359/
https://www.ncbi.nlm.nih.gov/pubmed/35879298
http://dx.doi.org/10.1038/s41467-022-31970-5

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