Cargando…

MYPT1 reduction is a pathogenic factor of erectile dysfunction

Erectile dysfunction (ED) is closely associated with smooth muscle dysfunction, but its underlying mechanisms remains incompletely understood. We here reported that the reduced expression of myosin phosphatase target subunit 1 (MYPT1), the main regulatory unit of myosin light chain phosphatase, was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Wei, Sun, Jie, Yao, Liang-Yu, Hang, Dong, Li, Ye-Qiong, Chen, Cai-Ping, Zhou, Yu-Wei, Chen, Xin, Tao, Tao, Wei, Li-Sha, Zheng, Yan-Yan, Ge, Xie, Li, Chao-Jun, Xin, Zhong-Cheng, Pan, Yang, Wang, Xin-Zhu, He, Wei-Qi, Zhang, Xue-Na, Yao, Bing, Zhu, Min-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314386/ https://www.ncbi.nlm.nih.gov/pubmed/35879418 http://dx.doi.org/10.1038/s42003-022-03716-y

Ejemplares similares

MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease
por: Zhao, W., et al.
Publicado: (2019)

Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy
por: Ma, Wei-Xing, et al.
Publicado: (2020)

Erectile dysfunction and exosome therapy
por: Feng, Huan, et al.
Publicado: (2023)

Pancreatic kininogenase improves erectile function in streptozotocin-induced type 2 diabetic rats with erectile dysfunction
por: Chen, Guo-Tao, et al.
Publicado: (2018)

Vacuum therapy ameliorates erectile dysfunction in bilateral cavernous nerve crush rats by inhibiting apoptosis and activating autophagy
por: Wu, Chang-Jing, et al.
Publicado: (2021)

A correlation study of ischiocavernosus muscle injury with different types of pelvic fractures and erectile dysfunction after pelvic fracture
por: Chen, Zongping, et al.
Publicado: (2020)

Erectile dysfunction and the risk of prostate cancer
por: Lin, Wei-Yu, et al.
Publicado: (2017)

Effects of major depression and bipolar disorder on erectile dysfunction: a two-sample mendelian randomization study
por: Chen, Wei-Kang, et al.
Publicado: (2023)

A higher TyG index is related with a higher prevalence of erectile dysfunction in males between the ages 20-70 in the United States, according to a cross-sectional research
por: Li, Lin, et al.
Publicado: (2022)

Efficacy and safety of aildenafil citrate in Chinese men with erectile dysfunction: a multicenter, randomized, double-blind, placebo-controlled crossover trial
por: Cui, Wan-Shou, et al.
Publicado: (2021)

Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke
por: Meng, Hailan, et al.
Publicado: (2021)

Acupuncture for Treatment of Erectile Dysfunction: A Systematic Review and Meta-Analysis
por: Lai, Bao-yong, et al.
Publicado: (2019)

Perception of the association between erectile dysfunction and cardiovascular disease among Chinese physicians: an online survey
por: Li, Dong-Jie, et al.
Publicado: (2020)

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction
por: Sun, Jie, et al.
Publicado: (2020)

The effect of erectile dysfunction on quality of life in male kidney transplant recipients
por: Wang, Wei-Gang, et al.
Publicado: (2014)

The association between heavy metal exposure and erectile dysfunction in the United States
por: Wang, Wei, et al.
Publicado: (2022)

Genetic Evidence Supporting a Causal Role of Snoring in Erectile Dysfunction
por: Xiong, Yang, et al.
Publicado: (2022)

Epalrestat, an Aldose Reductase Inhibitor, Restores Erectile Function in Streptozocin-induced Diabetic Rats
por: Yang, Bai-Bing, et al.
Publicado: (2018)

Erectile dysfunction is associated with subclinical carotid vascular disease in young men lacking widely-known risk factors
por: Yao, Feng-Juan, et al.
Publicado: (2018)

Correlation between gut microbiota diversity and psychogenic erectile dysfunction
por: Geng, Qiang, et al.
Publicado: (2021)

Association between coronary heart disease and erectile dysfunction in Chinese Han population
por: Tian, Guo-Xiang, et al.
Publicado: (2017)

Audiovisual Sexual Stimulation and RigiScan Test for the Diagnosis of Erectile Dysfunction
por: Wang, Tao, et al.
Publicado: (2018)

Avanafil for male erectile dysfunction: a systematic review and meta-analysis
por: Cui, Yuan-Shan, et al.
Publicado: (2014)

Correction: Epalrestat, an Aldose Reductase Inhibitor, Restores Erectile Function in Streptozocin-induced Diabetic Rats
por: Yang, Bai-Bing, et al.
Publicado: (2019)

Prevalence and Characteristics of Erectile Dysfunction in Obstructive Sleep Apnea Patients
por: Feng, Chen, et al.
Publicado: (2022)

AB231. The relationship between cardiovascular disease and erectile dysfunction among aged men in Southern China
por: Yan, Weixin, et al.
Publicado: (2016)

Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction
por: Qian, Xin, et al.
Publicado: (2023)

AB29. The experience in diagnosising and treating rare types of erectile dysfunction
por: Chen, Jun, et al.
Publicado: (2014)

Evolocumab attenuate pericoronary adipose tissue density via reduction of lipoprotein(a) in type 2 diabetes mellitus: a serial follow-up CCTA study
por: Yu, Meng-Meng, et al.
Publicado: (2023)

MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer
por: Lin, Zhuo-yuan, et al.
Publicado: (2017)

Erectile Dysfunction in Patients with Sleep Apnea – A Nationwide Population-Based Study
por: Chen, Chia-Min, et al.
Publicado: (2015)

The association between plant-based diet and erectile dysfunction in Chinese men
por: Lu, Yi, et al.
Publicado: (2021)

In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats
por: Zhang, Hai-Bo, et al.
Publicado: (2019)

Potential Effect of the Circadian Clock on Erectile Dysfunction
por: Li, Tao, et al.
Publicado: (2022)

Erectile Dysfunction Is Associated With Excessive Growth Hormone Levels in Male Patients With Acromegaly
por: Chen, Zhengyuan, et al.
Publicado: (2021)

Expression of MYPT1, CPI-17 and MLC20 in ileum of neonatal mouse NEC model and its significance
por: Yin, Yinyu, et al.
Publicado: (2017)

Correction to: MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer
por: Lin, Zhuo-yuan, et al.
Publicado: (2019)

Stem Cell Therapy for Erectile Dysfunction of Cavernous Nerve Injury Rats: A Systematic Review and Meta-Analysis
por: Shan, Haitao, et al.
Publicado: (2015)

The association between subclinical hypothyroidism and erectile dysfunction
por: Chen, Dawei, et al.
Publicado: (2018)

Reduction of Plasma Gelsolin Levels Correlates with Development of Multiple Organ Dysfunction Syndrome and Fatal Outcome in Burn Patients
por: Huang, Li-feng, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_oc2kdfp51660tckha3saplelrd