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A single immunization with a modified vaccinia Ankara vectored vaccine producing Sudan virus-like particles protects from lethal infection

A new vectored vaccine MVA-VLP-SUDV was generated against Sudan ebolavirus (SUDV) combining the advantages of the immunogenicity of a live attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conformation of virus-like particles (VLPs). The vaccine expresses minimal component...

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Detalles Bibliográficos
Autores principales:	Malherbe, Delphine C., Domi, Arban, Hauser, Mary J., Atyeo, Caroline, Fischinger, Stephanie, Hyde, Matthew A., Williams, Julie M., Alter, Galit, Guirakhoo, Farshad, Bukreyev, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314403/ https://www.ncbi.nlm.nih.gov/pubmed/35879311 http://dx.doi.org/10.1038/s41541-022-00512-x

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