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In vitro renal calculi destruction by a high-frequency glow discharge plasma

Despite the progress made in the treatment of nephrolithiasis, the existing methods of renal calculi destruction are not ideal and have both advantages and disadvantages. Considering the process of high-frequency glow discharge formation on the surface of an electrode and in an electrolyte solution,...

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Autores principales: Belov, Sergej V., Danileyko, Yury K., Pishchalnikov, Roman Y., Gudkov, Sergey V., Egorov, Alexej V., Lukanin, Vladimir I., Sidorov, Vladimir A., Tsvetkov, Vladimir B., Ali, Stanislav K., Kondrashev, Sergey V., Rotanov, Evgeny G., Shakhovskoy, Andrei V., Andreev, Stepan N., Bezrukov, Evgeny A., Glybochko, Petr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314433/
https://www.ncbi.nlm.nih.gov/pubmed/35879389
http://dx.doi.org/10.1038/s41598-022-16702-5
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author Belov, Sergej V.
Danileyko, Yury K.
Pishchalnikov, Roman Y.
Gudkov, Sergey V.
Egorov, Alexej V.
Lukanin, Vladimir I.
Sidorov, Vladimir A.
Tsvetkov, Vladimir B.
Ali, Stanislav K.
Kondrashev, Sergey V.
Rotanov, Evgeny G.
Shakhovskoy, Andrei V.
Andreev, Stepan N.
Bezrukov, Evgeny A.
Glybochko, Petr V.
author_facet Belov, Sergej V.
Danileyko, Yury K.
Pishchalnikov, Roman Y.
Gudkov, Sergey V.
Egorov, Alexej V.
Lukanin, Vladimir I.
Sidorov, Vladimir A.
Tsvetkov, Vladimir B.
Ali, Stanislav K.
Kondrashev, Sergey V.
Rotanov, Evgeny G.
Shakhovskoy, Andrei V.
Andreev, Stepan N.
Bezrukov, Evgeny A.
Glybochko, Petr V.
author_sort Belov, Sergej V.
collection PubMed
description Despite the progress made in the treatment of nephrolithiasis, the existing methods of renal calculi destruction are not ideal and have both advantages and disadvantages. Considering the process of high-frequency glow discharge formation on the surface of an electrode and in an electrolyte solution, we obtained the results on the destruction of renal calculi in vitro. It was shown that the destruction of kidney stones by glow discharge plasma was caused by several processes—the plasma induced effect of hydrated electrons and shock wave effect of the electrolyte stimulated by electrical breakdowns in the plasma. The plasma generation modes were configured by estimating the thickness of the vapor–gas layer in which the plasma burns. Thus, the average rate of contact destruction of renal calculi was measured depending on the plasma generator input power and time of plasma exposure. We conclude that the method of stone fragmentation by high-frequency electrolyte plasma is rather perspective and can be used in endoscopic urology for percutaneous and transurethral lithotripsy.
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spelling pubmed-93144332022-07-27 In vitro renal calculi destruction by a high-frequency glow discharge plasma Belov, Sergej V. Danileyko, Yury K. Pishchalnikov, Roman Y. Gudkov, Sergey V. Egorov, Alexej V. Lukanin, Vladimir I. Sidorov, Vladimir A. Tsvetkov, Vladimir B. Ali, Stanislav K. Kondrashev, Sergey V. Rotanov, Evgeny G. Shakhovskoy, Andrei V. Andreev, Stepan N. Bezrukov, Evgeny A. Glybochko, Petr V. Sci Rep Article Despite the progress made in the treatment of nephrolithiasis, the existing methods of renal calculi destruction are not ideal and have both advantages and disadvantages. Considering the process of high-frequency glow discharge formation on the surface of an electrode and in an electrolyte solution, we obtained the results on the destruction of renal calculi in vitro. It was shown that the destruction of kidney stones by glow discharge plasma was caused by several processes—the plasma induced effect of hydrated electrons and shock wave effect of the electrolyte stimulated by electrical breakdowns in the plasma. The plasma generation modes were configured by estimating the thickness of the vapor–gas layer in which the plasma burns. Thus, the average rate of contact destruction of renal calculi was measured depending on the plasma generator input power and time of plasma exposure. We conclude that the method of stone fragmentation by high-frequency electrolyte plasma is rather perspective and can be used in endoscopic urology for percutaneous and transurethral lithotripsy. Nature Publishing Group UK 2022-07-25 /pmc/articles/PMC9314433/ /pubmed/35879389 http://dx.doi.org/10.1038/s41598-022-16702-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Belov, Sergej V.
Danileyko, Yury K.
Pishchalnikov, Roman Y.
Gudkov, Sergey V.
Egorov, Alexej V.
Lukanin, Vladimir I.
Sidorov, Vladimir A.
Tsvetkov, Vladimir B.
Ali, Stanislav K.
Kondrashev, Sergey V.
Rotanov, Evgeny G.
Shakhovskoy, Andrei V.
Andreev, Stepan N.
Bezrukov, Evgeny A.
Glybochko, Petr V.
In vitro renal calculi destruction by a high-frequency glow discharge plasma
title In vitro renal calculi destruction by a high-frequency glow discharge plasma
title_full In vitro renal calculi destruction by a high-frequency glow discharge plasma
title_fullStr In vitro renal calculi destruction by a high-frequency glow discharge plasma
title_full_unstemmed In vitro renal calculi destruction by a high-frequency glow discharge plasma
title_short In vitro renal calculi destruction by a high-frequency glow discharge plasma
title_sort in vitro renal calculi destruction by a high-frequency glow discharge plasma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314433/
https://www.ncbi.nlm.nih.gov/pubmed/35879389
http://dx.doi.org/10.1038/s41598-022-16702-5
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