Primary thyroid gland myxofibrosarcoma: a case report and review of the literature

BACKGROUND: Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. CASE PRESENTATION: We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a...

Descripción completa

Detalles Bibliográficos
Autores principales: Stylianidi, Maria Chara, Haeberle, Lena, Schott, Matthias, Mori, Yuriko, Antke, Christina, Giesel, Frederick Lars, Antoch, Gerald, Esposito, Irene, Knoefel, Wolfram Trudo, Krieg, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314473/
https://www.ncbi.nlm.nih.gov/pubmed/35876910
http://dx.doi.org/10.1186/s40792-022-01496-5
Descripción
Sumario:BACKGROUND: Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. CASE PRESENTATION: We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a hypoechoic thyroid nodule with microcalcifications that was highly suspicious for malignancy. He underwent a left hemithyroidectomy. Histopathological examination and immunohistochemical studies revealed a myxofibrosarcoma of the thyroid gland. CONCLUSION: Myxofibrosarcoma of the thyroid gland is extremely rare. The diagnosis is based on histopathological features. Radical surgery achieving tumor-free resection margins remains the only chance for cure. However, the role of radiotherapy and/or chemotherapy is still under debate. Due to their high tendency for locoregional recurrence, a close follow-up after surgery is mandatory.

Ejemplares similares