Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity

Human milk contains three antibody classes that confer mucosal immunity to the breastfed infant: secretory IgA (SIgA), secretory IgM (SIgM), and IgG. Influenza and pertussis vaccines administered during pregnancy induce pathogen specific SIgA and IgG responses in human milk that have been shown to p...

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Autores principales: Hunagund, Soumya, Golan, Yarden, Asiodu, Ifeyinwa V., Prahl, Mary, Gaw, Stephanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314549/
https://www.ncbi.nlm.nih.gov/pubmed/35903100
http://dx.doi.org/10.3389/fimmu.2022.910383
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author Hunagund, Soumya
Golan, Yarden
Asiodu, Ifeyinwa V.
Prahl, Mary
Gaw, Stephanie L.
author_facet Hunagund, Soumya
Golan, Yarden
Asiodu, Ifeyinwa V.
Prahl, Mary
Gaw, Stephanie L.
author_sort Hunagund, Soumya
collection PubMed
description Human milk contains three antibody classes that confer mucosal immunity to the breastfed infant: secretory IgA (SIgA), secretory IgM (SIgM), and IgG. Influenza and pertussis vaccines administered during pregnancy induce pathogen specific SIgA and IgG responses in human milk that have been shown to protect the breastfed infant from these respiratory illnesses. In addition, mRNA vaccines against the SARS-CoV-2 virus administered during pregnancy and lactation induce anti-SARS-CoV-2 IgG and IgA responses in human milk. This review summarizes the immunologic benefits of influenza, pertussis, and COVID-19 vaccines conferred by human milk. Additionally, future research direction in human milk immunity and public health needs to improve lactational support are discussed.
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spelling pubmed-93145492022-07-27 Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity Hunagund, Soumya Golan, Yarden Asiodu, Ifeyinwa V. Prahl, Mary Gaw, Stephanie L. Front Immunol Immunology Human milk contains three antibody classes that confer mucosal immunity to the breastfed infant: secretory IgA (SIgA), secretory IgM (SIgM), and IgG. Influenza and pertussis vaccines administered during pregnancy induce pathogen specific SIgA and IgG responses in human milk that have been shown to protect the breastfed infant from these respiratory illnesses. In addition, mRNA vaccines against the SARS-CoV-2 virus administered during pregnancy and lactation induce anti-SARS-CoV-2 IgG and IgA responses in human milk. This review summarizes the immunologic benefits of influenza, pertussis, and COVID-19 vaccines conferred by human milk. Additionally, future research direction in human milk immunity and public health needs to improve lactational support are discussed. Frontiers Media S.A. 2022-07-12 /pmc/articles/PMC9314549/ /pubmed/35903100 http://dx.doi.org/10.3389/fimmu.2022.910383 Text en Copyright © 2022 Hunagund, Golan, Asiodu, Prahl and Gaw https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Hunagund, Soumya
Golan, Yarden
Asiodu, Ifeyinwa V.
Prahl, Mary
Gaw, Stephanie L.
Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title_full Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title_fullStr Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title_full_unstemmed Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title_short Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity
title_sort effects of vaccination against influenza, pertussis, and covid-19 on human milk antibodies: current evidence and implications for health equity
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314549/
https://www.ncbi.nlm.nih.gov/pubmed/35903100
http://dx.doi.org/10.3389/fimmu.2022.910383
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