Single-Cell Transcriptomic Analysis Reveals the Crosstalk Propensity Between the Tumor Intermediate State and the CD8+ T Exhausted State to be Associated with Clinical Benefits in Melanoma

Heterogeneous crosstalk between tumor cells and CD8+ T cells leads to substantial variation in clinical benefits from immunotherapy in melanoma. Due to spatial distribution and functional state heterogeneity, it is still unknown whether there is a crosstalk propensity between tumor cells and CD8+ T...

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Detalles Bibliográficos
Autores principales: Zhu, Jiali, Yan, Min, Yan, Haoteng, Xu, Liwen, Jiang, Zedong, Liao, Gaoming, Zhou, Yao, Liu, Wei, Liang, Xin, Li, Xia, Xiao, Yun, Zhang, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314667/
https://www.ncbi.nlm.nih.gov/pubmed/35903095
http://dx.doi.org/10.3389/fimmu.2022.766852

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