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Structure‐Guided Modulation of the Catalytic Properties of [2Fe−2S]‐Dependent Dehydratases

The FeS cluster‐dependent dihydroxyacid dehydratases (DHADs) and sugar acid‐specific dehydratases (DHTs) from the ilvD/EDD superfamily are key enzymes in the bioproduction of a wide variety of chemicals. We analyzed [2Fe−2S]‐dependent dehydratases in silico and in vitro, deduced functionally relevan...

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Detalles Bibliográficos
Autores principales:	Melse, Okke, Sutiono, Samuel, Haslbeck, Magdalena, Schenk, Gerhard, Antes, Iris, Sieber, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314677/ https://www.ncbi.nlm.nih.gov/pubmed/35263023 http://dx.doi.org/10.1002/cbic.202200088

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