Cargando…

The aqueous stability and interactions of organoruthenium compounds with serum proteins, cell culture medium, and human serum

Metal complexes bind to a wide variety of biomolecules and the control of the reactivity is essential when designing anticancer metallodrugs with a specific mode of action in mind. In this study, we used the highly cytotoxic compound [Ru(II)(cym)(8-HQ)Cl] (cym = η(6)-p-cymene, 8-HQ = 8-hydroxyquinol...

Descripción completa

Detalles Bibliográficos
Autores principales: Riisom, Mie, Eade, Liam, Tremlett, William D J, Hartinger, Christian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314723/
https://www.ncbi.nlm.nih.gov/pubmed/35751650
http://dx.doi.org/10.1093/mtomcs/mfac043