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The aqueous stability and interactions of organoruthenium compounds with serum proteins, cell culture medium, and human serum
Metal complexes bind to a wide variety of biomolecules and the control of the reactivity is essential when designing anticancer metallodrugs with a specific mode of action in mind. In this study, we used the highly cytotoxic compound [Ru(II)(cym)(8-HQ)Cl] (cym = η(6)-p-cymene, 8-HQ = 8-hydroxyquinol...
Autores principales: | Riisom, Mie, Eade, Liam, Tremlett, William D J, Hartinger, Christian G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314723/ https://www.ncbi.nlm.nih.gov/pubmed/35751650 http://dx.doi.org/10.1093/mtomcs/mfac043 |
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