Disrupting Transcription and Folate Biosynthesis Leads to Synergistic Suppression of Escherichia coli Growth

The use of synergistic antibiotic combinations has emerged as a viable approach to contain the rapid spread of antibiotic‐resistant pathogens. Here we report the discovery of a new strongly synergistic pair – microcin J25 and sulfamonomethoxine. The former is a lasso peptide that inhibits the functi...

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Detalles Bibliográficos
Autores principales: Chen, Pei‐Hsin, Sung, Li‐Kang, Hegemann, Julian D., Chu, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314896/
https://www.ncbi.nlm.nih.gov/pubmed/35201676
http://dx.doi.org/10.1002/cmdc.202200075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314896/
https://www.ncbi.nlm.nih.gov/pubmed/35201676
http://dx.doi.org/10.1002/cmdc.202200075

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