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Disrupting Transcription and Folate Biosynthesis Leads to Synergistic Suppression of Escherichia coli Growth
The use of synergistic antibiotic combinations has emerged as a viable approach to contain the rapid spread of antibiotic‐resistant pathogens. Here we report the discovery of a new strongly synergistic pair – microcin J25 and sulfamonomethoxine. The former is a lasso peptide that inhibits the functi...
Autores principales: | Chen, Pei‐Hsin, Sung, Li‐Kang, Hegemann, Julian D., Chu, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314896/ https://www.ncbi.nlm.nih.gov/pubmed/35201676 http://dx.doi.org/10.1002/cmdc.202200075 |
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