The earliest events in BRAF ‐mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways

Around 15–30% of colorectal cancers (CRC) develop from sessile serrated lesions (SSLs). After many years of indolent growth, SSLs can develop dysplasia and rapidly progress to CRC through events that are only partially understood. We studied molecular events at the very early stages of progression o...

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Detalles Bibliográficos
Autores principales: Bleijenberg, Arne GC, IJspeert, Joep EG, Mulder, Jos BG, Drillenburg, Paul, Stel, Herbert V, Lodder, Elisabeth M, Carvalho, Beatriz, Jansen, Jade, Meijer, Gerrit, van Eeden, Susanne, Dekker, Evelien, van Noesel, Carel JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314978/
https://www.ncbi.nlm.nih.gov/pubmed/35143042
http://dx.doi.org/10.1002/path.5881

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