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Fermentative Production of Halogenated Tryptophan Derivatives with Corynebacterium glutamicum Overexpressing Tryptophanase or Decarboxylase Genes

The aromatic amino acid l‐tryptophan serves as a precursor for many valuable compounds such as neuromodulators, indoleamines and indole alkaloids. In this work, tryptophan biosynthesis was extended by halogenation followed by decarboxylation to the respective tryptamines or cleavage to the respectiv...

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Detalles Bibliográficos
Autores principales: Kerbs, Anastasia, Burgardt, Arthur, Veldmann, Kareen H., Schäffer, Thomas, Lee, Jin‐Ho, Wendisch, Volker F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315010/
https://www.ncbi.nlm.nih.gov/pubmed/35224830
http://dx.doi.org/10.1002/cbic.202200007