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Serological Biomarkers of Intestinal Collagen Turnover Identify Early Response to Infliximab Therapy in Patients With Crohn’s Disease

BACKGROUND: Crohn’s disease (CD) is characterized by excessive protease activity and extracellular matrix (ECM) remodeling. To date, 30–50% of patients experience non-response to anti-TNF-α treatment. This study aimed to assess whether serological biomarkers of ECM turnover could monitor or predict...

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Detalles Bibliográficos
Autores principales:	Alexdottir, Marta S., Bourgonje, Arno R., Karsdal, Morten A., Pehrsson, Martin, Loveikyte, Roberta, van Dullemen, Hendrik M., Visschedijk, Marijn C., Festen, Eleonora A. M., Weersma, Rinse K., Faber, Klaas Nico, Dijkstra, Gerard, Mortensen, Joachim H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315105/ https://www.ncbi.nlm.nih.gov/pubmed/35903311 http://dx.doi.org/10.3389/fmed.2022.933872

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