Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs

Recent evidence indicates that RNA‐dependent RNA polymerase (RdRP) activity of human telomerase reverse transcriptase (hTERT) regulates expression of target genes and is directly involved in tumor formation in a telomere‐independent manner. Non‐canonical function of hTERT has been considered as a th...

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Detalles Bibliográficos
Autores principales: Matsuda, Yoko, Yamashita, Taro, Ye, Juanjuan, Yasukawa, Mami, Yamakawa, Keiko, Mukai, Yuri, Machitani, Mitsuhiro, Daigo, Yataro, Miyagi, Yohei, Yokose, Tomoyuki, Oshima, Takashi, Ito, Hiroyuki, Morinaga, Soichiro, Kishida, Takeshi, Minamoto, Toshinari, Yamada, Shinji, Takei, Junko, Kaneko, Mika K, Kojima, Motohiro, Kaneko, Shuichi, Masaki, Tsutomu, Hirata, Masahiro, Haba, Reiji, Kontani, Keiichi, Kanaji, Nobuhiro, Miyatake, Nobuyuki, Okano, Keiichi, Kato, Yukinari, Masutomi, Kenkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315154/
https://www.ncbi.nlm.nih.gov/pubmed/35094384
http://dx.doi.org/10.1002/path.5876

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