The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations

OBJECTIVE: While most of the variation in thyroid function is determined by genetic factors, single nucleotide polymorphisms (SNPs) identified via genome-wide association analyses have only explained ~5% to 9% of this variance so far. Most SNPs were in or nearby genes with no known role in thyroid h...

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Detalles Bibliográficos
Autores principales: Sterenborg, Rosalie B T M, Galesloot, Tessel E, Teumer, Alexander, Netea-Maier, Romana T, Speed, Doug, Meima, Marcel E, Visser, W Edward, Smit, Johannes W A, Peeters, Robin P, Medici, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315164/
https://www.ncbi.nlm.nih.gov/pubmed/35262175
http://dx.doi.org/10.1210/clinem/dgac136

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