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Effect of siponimod on magnetic resonance imaging measures of neurodegeneration and myelination in secondary progressive multiple sclerosis: Gray matter atrophy and magnetization transfer ratio analyses from the EXPAND phase 3 trial

BACKGROUND: Magnetic resonance imaging (MRI) measurements of gray matter (GM) atrophy and magnetization transfer ratio (MTR; correlate of myelination) may provide better insights than conventional MRI regarding brain tissue integrity/myelination in multiple sclerosis (MS). OBJECTIVE: To examine the...

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Detalles Bibliográficos
Autores principales: Arnold, Douglas L, Piani-Meier, Daniela, Bar-Or, Amit, Benedict, Ralph HB, Cree, Bruce AC, Giovannoni, Gavin, Gold, Ralf, Vermersch, Patrick, Arnould, Sophie, Dahlke, Frank, Hach, Thomas, Ritter, Shannon, Karlsson, Göril, Kappos, Ludwig, Fox, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315182/
https://www.ncbi.nlm.nih.gov/pubmed/35261318
http://dx.doi.org/10.1177/13524585221076717