Mapping CAR T-Cell Design Space Using Agent-Based Models

Chimeric antigen receptor (CAR) T-cell therapy shows promise for treating liquid cancers and increasingly for solid tumors as well. While potential design strategies exist to address translational challenges, including the lack of unique tumor antigens and the presence of an immunosuppressive tumor...

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Detalles Bibliográficos
Autores principales: Prybutok, Alexis N., Yu, Jessica S., Leonard, Joshua N., Bagheri, Neda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315201/
https://www.ncbi.nlm.nih.gov/pubmed/35903149
http://dx.doi.org/10.3389/fmolb.2022.849363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315201/
https://www.ncbi.nlm.nih.gov/pubmed/35903149
http://dx.doi.org/10.3389/fmolb.2022.849363

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