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Mapping CAR T-Cell Design Space Using Agent-Based Models
Chimeric antigen receptor (CAR) T-cell therapy shows promise for treating liquid cancers and increasingly for solid tumors as well. While potential design strategies exist to address translational challenges, including the lack of unique tumor antigens and the presence of an immunosuppressive tumor...
Autores principales: | Prybutok, Alexis N., Yu, Jessica S., Leonard, Joshua N., Bagheri, Neda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315201/ https://www.ncbi.nlm.nih.gov/pubmed/35903149 http://dx.doi.org/10.3389/fmolb.2022.849363 |
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