Cargando…

Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression

Hypopharyngeal squamous cell carcinoma (HSCC) is one of the high mortality cancers with a poor prognosis, which is driving the development of new chemotherapeutic agents. We identified the anticancer effects of a natural compound, solamargine (SM), on FaDU cells and explored its mechanism in terms o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Ying, Jin, Mengli, Yuan, Dai, Zhao, Yicheng, Kong, Xiangri, Guo, Xuerui, Wang, Xingye, Hou, Juan, Wang, Bingmei, Song, Wu, Tang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315292/ https://www.ncbi.nlm.nih.gov/pubmed/35903338 http://dx.doi.org/10.3389/fphar.2022.887387

Ejemplares similares

lncRNA HOXA11-AS Promotes Proliferation and Migration via Sponging miR-155 in Hypopharyngeal Squamous Cell Carcinoma
por: Xu, Jianing, et al.
Publicado: (2020)

HOXA11 antisense long noncoding RNA (HOXA11‐AS): A promising lncRNA in human cancers
por: Lu, Cheng‐Wei, et al.
Publicado: (2018)

Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection
por: Jing, Shisong, et al.
Publicado: (2022)

LncRNA PTCSC3 Alleviates the Postoperative Distant Recurrence of Gastric Cancer by Suppression of lncRNA HOXA11-AS
por: Xu, Jiapeng, et al.
Publicado: (2020)

The Polymorphisms of lncRNA HOXA11-AS and the risk of Lung Cancer in Northeastern Chinese population
por: Gao, Min, et al.
Publicado: (2020)

Identification of solamargine as a cisplatin sensitizer through phenotypical screening in cisplatin-resistant NSCLC organoids
por: Han, Yi, et al.
Publicado: (2022)

Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE
por: Xu, Yetao, et al.
Publicado: (2018)

The integrated comprehension of lncRNA HOXA-AS3 implication on human diseases
por: Yao, Qinfan, et al.
Publicado: (2022)

Increased response to TPF chemotherapy promotes immune escape in hypopharyngeal squamous cell carcinoma
por: Li, Ruichen, et al.
Publicado: (2023)

LncRNA HOXA11-AS Promotes Proliferation and Cisplatin Resistance of Oral Squamous Cell Carcinoma by Suppression of miR-214-3p Expression
por: Wang, Xiaoyan, et al.
Publicado: (2019)

LncRNA HOXA11‐AS promotes hepatocellular carcinoma progression by repressing miR‐214‐3p
por: Zhan, Meixiao, et al.
Publicado: (2018)

LncRNA NR120519 Blocks KRT17 to Promote Cell Proliferation and Migration in Hypopharyngeal Squamous Carcinoma
por: Zhou, Zheng, et al.
Publicado: (2023)

Silencing lncRNA HOXA10-AS decreases cell proliferation of oral cancer and HOXA10-antisense RNA can serve as a novel prognostic predictor
por: Yan, Xiaodong, et al.
Publicado: (2020)

Clinical Significance and Effect of lncRNA HOXA11-AS in NSCLC: A Study Based on Bioinformatics, In Vitro and in Vivo Verification
por: Zhang, Yu, et al.
Publicado: (2017)

Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Signature in Head and Neck Squamous Cell Carcinoma
por: Pan, Yunbao, et al.
Publicado: (2019)

LncRNA HOXA-AS2 Promotes Tumor Progression by Suppressing miR-567 Expression in Oral Squamous Cell Carcinoma
por: Chen, Rui, et al.
Publicado: (2021)

Identification of lncRNA Signature of Tumor-Infiltrating T Lymphocytes With Potential Implications for Prognosis and Chemotherapy of Head and Neck Squamous Cell Carcinoma
por: Wang, Liping, et al.
Publicado: (2022)

Overexpression of lncRNA HOXA-AS2 promotes the progression of oral squamous cell carcinoma by mediating SNX5 expression
por: Li, Zhangyi
Publicado: (2022)

A novel necroptosis-related LncRNA signature for prediction of prognosis and therapeutic responses of head and neck squamous cell carcinoma
por: Meng, Zilu, et al.
Publicado: (2022)

PRMT5 Prevents Cardiomyocyte Hypertrophy via Symmetric Dimethylating HoxA9 and Repressing HoxA9 Expression
por: Cai, Sidong, et al.
Publicado: (2020)

Modular scaffolding by lncRNA HOXA10-AS promotes oral cancer progression
por: Chen, Yi-Tung, et al.
Publicado: (2022)

LncRNA HOXA-AS3 confers cisplatin resistance by interacting with HOXA3 in non-small-cell lung carcinoma cells
por: Lin, Shuang, et al.
Publicado: (2019)

An m6A-Related lncRNA Signature Predicts the Prognosis of Hepatocellular Carcinoma
por: Zhang, Zhenyu, et al.
Publicado: (2022)

Identification of a novel lncRNA prognostic signature and analysis of functional lncRNA AC115619.1 in hepatocellular carcinoma
por: Gan, Binliang, et al.
Publicado: (2023)

LncRNA Profile Study Reveals a Three-LncRNA Signature Associated With the Pathological Complete Response Following Neoadjuvant Chemotherapy in Breast Cancer
por: Zeng, Ying, et al.
Publicado: (2019)

LncRNA HOXA-AS2 Promotes Oral Squamous Cell Proliferation, Migration, and Invasion via Upregulating EZH2 as an Oncogene
por: Zhao, Zhen, et al.
Publicado: (2021)

Time-course differential lncRNA and mRNA expressions in radioresistant hypopharyngeal cancer cells
por: Zhou, Jieyu, et al.
Publicado: (2017)

LncRNA HOTTIP-Mediated HOXA11 Expression Promotes Cell Growth, Migration and Inhibits Cell Apoptosis in Breast Cancer
por: Sun, Yanqin, et al.
Publicado: (2018)

Novel reciprocal interaction of lncRNA HOTAIR and miR‐214‐3p contribute to the solamargine‐inhibited PDPK1 gene expression in human lung cancer
por: Tang, Qing, et al.
Publicado: (2019)

Solamargine inhibits gastric cancer progression by regulating the expression of lncNEAT1_2 via the MAPK signaling pathway
por: Fu, Runjia, et al.
Publicado: (2019)

Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition
por: Li, Wenlei, et al.
Publicado: (2017)

Molecular Characterization and Biological Function of a Novel LncRNA CRNG in Swine
por: Lu, Qirong, et al.
Publicado: (2019)

ARID1B/SUB1‐activated lncRNA HOXA‐AS2 drives the malignant behaviour of hepatoblastoma through regulation of HOXA3
por: Liu, Gongbao, et al.
Publicado: (2021)

The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma
por: Cao, Kun, et al.
Publicado: (2019)

LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation
por: Shao, Ming, et al.
Publicado: (2018)

Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10
por: Cheng, Jing, et al.
Publicado: (2022)

LncRNA HOXA11‐AS promotes vascular endothelial cell injury in atherosclerosis by regulating the miR‐515‐5p/ROCK1 axis
por: Gao, Feng, et al.
Publicado: (2022)

LncRNA HOTAIRM1/HOXA1 Axis Promotes Cell Proliferation, Migration And Invasion In Endometrial Cancer
por: Li, Xianli, et al.
Publicado: (2019)

Identification of Hub lncRNAs Along With lncRNA-miRNA-mRNA Network for Effective Diagnosis and Prognosis of Papillary Thyroid Cancer
por: Li, Haiyan, et al.
Publicado: (2021)

Effects of lncRNA HOXA11-AS on Sevoflurane-Induced Neuronal Apoptosis and Inflammatory Responses by Regulating miR-98-5p/EphA4
por: Zhao, Li, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k9m8r6p3iok0r4drculr9tki17