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The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide

The disruption of neurodevelopment is a hypothesis for the emergence of schizophrenia. Some evidence supports the hypothesis that a redox imbalance could account for the developmental impairments associated with schizophrenia. Additionally, there is a deficit in glutathione (GSH), a main antioxidant...

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Detalles Bibliográficos
Autores principales: Lopes-Rocha, Ana, Bezerra, Thiago Ohno, Zanotto, Roberta, Lages Nascimento, Inda, Rodrigues, Angela, Salum, Cristiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315304/
https://www.ncbi.nlm.nih.gov/pubmed/35903343
http://dx.doi.org/10.3389/fphar.2022.924955