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The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide
The disruption of neurodevelopment is a hypothesis for the emergence of schizophrenia. Some evidence supports the hypothesis that a redox imbalance could account for the developmental impairments associated with schizophrenia. Additionally, there is a deficit in glutathione (GSH), a main antioxidant...
Autores principales: | Lopes-Rocha, Ana, Bezerra, Thiago Ohno, Zanotto, Roberta, Lages Nascimento, Inda, Rodrigues, Angela, Salum, Cristiane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315304/ https://www.ncbi.nlm.nih.gov/pubmed/35903343 http://dx.doi.org/10.3389/fphar.2022.924955 |
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